Utilization of iron dextran.

نویسندگان

  • A G Davies
  • M R Beamish
  • A Jacobs
چکیده

The utilization of iron dextran was investigated in normal subjects, in patients with iron-deficiency anaemia, and in anaemias associated with rheumatoid arthritis, reticulosis, and uraemia. Utilization of iron for haemoglobin formation at 14 days was found to be depressed in patients with rheumatoid arthritis, reticulosis, and uraemia, but when a concomitant iron-deficiency anaemia was present utilization was significantly increased. When iron dextran is used to treat anaemias in such conditions an optimum therapeutic response will be obtained only when bone marrow iron stores are absent.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Dextran grafted nickel-doped superparamagnetic iron oxide nanoparticles: Electrochemical synthesis and characterization

In this paper, polymer grafted nickel-doped iron oxide nanoparticles are fabricated via an easy, one-step and fast electrochemical procedure. In the deposition experiments, iron(II) chloride hexahydrate, iron(III) nitrate nonahydrate, nickel chloride hexahydrate, and dextran were used as the bath composition. Dextran grafted nickel-doped iron oxides (DEX/Ni-SPIOs) were synthesized with applying...

متن کامل

Simultaneous measurement of allantoin and urate in plasma: analytical evaluation and potential clinical application in oxidant:antioxidant balance studies.

pharmacological basis of therapeutics, 9th ed. New York: McGraw-Hill, 1996:1311–40. 7. Henderson PA, Hillman RS. Characteristics of iron dextran utilization in man. Blood 1969;34:357–75. 8. American Regent Laboratories. Dexferrum, iron dextran injection, USP. Package insert. Shirley, NY: American Regent Laboratories, 1996. 9. Nissenson AR, Lindsay RM, Swan S, Seligman PA, Strobos J. Sodium ferr...

متن کامل

Clinical studies on iron kinetics. II. Iron-kinetics studies in patients with malignant neoplasms. With special references to ferrokinetics and 59Fe labeled iron-dextran studies.

Although extensive studies on the anemia and iron metabolism in patients with malignant neoplasms have been made, the pathogenesis of the anemia ob· served in cancer patients remains obscure. The first purpose of this paper is to elucidate the functional impairment in red cell production in patients with malignant neoplasm by means of ferrokinetic studies. The second one· is to clarify how the ...

متن کامل

The Cytotoxicity of Dextran-coated Iron Oxide Nanoparticles on Hela and MCF-7 Cancerous Cell Lines

Background: Recently, iron oxide nanoparticles have attracted attention in various diagnosis and treatment fields. The aim of the present study was to investigate the cytotoxicity of various concentrations and incubation times of dextran-coated iron oxide nanoparticles (DIONPs) on HeLa and MCF-7 cancerous cell lines. Methods: This in-vitro study was conducted at Pharmaceutical Sciences Researc...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:
  • British medical journal

دوره 1 5741  شماره 

صفحات  -

تاریخ انتشار 1971